Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40718 | 0.78 | THRB (0.67) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| SCHEMBL146669 | 0.76 | THRB (0.63) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| Benzene SCHEMBL28307095 | 0.74 | HCAR2 (0.65) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| SCHEMBL28230354 | 0.74 | HCAR2 (0.65) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| SCHEMBL34054 | 0.74 | HCAR2 (0.65) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| Carbon Monoxide SCHEMBL10707595 | 0.74 | THRB (0.61) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| Ethylene Glycol SCHEMBL6491859 | 0.74 | THRB (0.61) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| SCHEMBL9164139 | 0.74 | TSHR (0.63) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| SCHEMBL147883 | 0.74 | THRB (0.61) | THRBHCAR2AKR1B10AKR1B1LMNA | |
| SCHEMBL434741 | 0.73 | TDP1 (0.74) | THRBHCAR2TDP1AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110785159-A | Dual paste type dental curable composition | 可乐丽则武齿科株式会社 | 2020-02-11 | — | — | CN | claimed |
| CN-110785159-A | Dual paste type dental curable composition | 可乐丽则武齿科株式会社 | 2020-02-11 | — | — | CN | disclosed |