SCHEMBL146669

SCHEMBL146669

C=CC(=O)OCCCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.63
LMNA P02545 1/20 0.62
AKR1B10 O60218 4/20 0.58
AKR1B1 P15121 4/20 0.58
SMN1; SMN2 Q16637 3/20 0.55
NPC1 O15118 1/20 0.55
RECQL P46063 1/20 0.55
RAB9A P51151 1/20 0.55
ALDH1A1 P00352 4/20 0.55
TSHR P16473 4/20 0.55
CYP3A4 P08684 1/20 0.55
HCAR2 Q8TDS4 1/20 0.54
ALOX5 P09917 1/20 0.51
TP53 P04637 2/20 0.50
HIF1A Q16665 2/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27929355 0.97 THRB (0.59) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
Acetic Acid SCHEMBL28013203 0.95 THRB (0.58) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
Formic Acid SCHEMBL28238298 0.95 THRB (0.58) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
SCHEMBL147883 0.95 THRB (0.61) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
Sulfuric Acid SCHEMBL28055049 0.94 THRB (0.56) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
SCHEMBL27759950 0.94 THRB (0.56) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
SCHEMBL28021234 0.94 THRB (0.56) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
SCHEMBL234455 0.93 ALDH1A1 (0.61) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
SCHEMBL233466 0.93 ALDH1A1 (0.61) THRBLMNAAKR1B10AKR1B1SMN1; SMN2
SCHEMBL342699 0.93 ALDH1A1 (0.61) THRBLMNAAKR1B10AKR1B1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1033 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
US-20250073018-A1 OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2025-03-06 US claimed
WO-2025045458-A1 OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX BAUSCH + LOMB IRELAND LIMITED (IE) 2025-03-06 WO claimed
CN-119431642-A Resin particle composition, detection kit, and method for producing resin particle composition 赛登化学株式会社 2025-02-14 CN claimed
CN-119391032-A Preparation and application of zwitterionic polymer monomer modified soft hydrophobic acrylate copolymer 厦门大学 2025-02-07 CN claimed
US-20250043103-A1 RESIN PARTICLE COMPOSITION, TEST KIT, AND MANUFACTURING METHOD OF RESIN PARTICLE COMPOSITION SAIDEN CHEMICAL INDUSTRY CO., LTD. (JP) 2025-02-06 US claimed
EP-4501971-A1 RESIN PARTICLE COMPOSITION, TEST KIT, AND MANUFACTURING METHOD OF RESIN PARTICLE COMPOSITION Saiden Chemical Industry Co., Ltd. (JP) 2025-02-05 EP claimed
CN-115298573-B High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2024-09-06 CN claimed
CN-118388701-A Solvent-free high-viscosity high-strength hydrophobic ion conductive elastomer and preparation method thereof 南京邮电大学 2024-07-26 CN claimed
EP-0543881-B1 SINGLE LAYER DRY PROCESSIBLE PHOTOSENSITIVE COMPOSITION AND TONING PROCESS DU PONT (US) 1995-06-28 EP claimed
US-5286604-A Single layer dry processible photothermal-sensitive element E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-15 US claimed
US-5258355-A Graft polymer with unsaturated ester groups forming shells AGFA-GEVAERT AKTIENGESELLSCHAFT 1993-11-02 US claimed
US-5229244-A Dry processible photosensitive composition including photo-acid generator and optically clear polymer (co-polymer) blend that becomes tacky upon exposure to actinic radiation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-20 US claimed
US-5139882-A Copolymer of acrylic acid ester, acrylic acid aromatic ester, and optionally carboxylic acid or ureido compound ROHM GMBH CHEMISCHE FABRIK (DE) 1992-08-18 US claimed
US-4987048-A NONSILVER PHOTOGRAPHY FOR COLOR PROOFING FUJI PHOTO FILM CO., LTD. (JP) 1991-01-22 US claimed
EP-0079057-B1 PRESENSITIZED LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1985-09-11 EP claimed
US-4478930-A SILVER AND NON-SILVER LAYERS; ACRYLIC AND METHACRYLIC COPOLYMERS DISPERSED IN COLLOID LAYER FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 US claimed
EP-0079057-A1 Presensitized lithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1983-05-18 EP claimed
US-4139391-A AN UNSATURATED COMPOUND, A PHOTOINITIATOR AND AN ACRYLIC OR METHACRYLIC ACID COPOLYMER WITH AN ACRYLIC OR METHACRYLIC ESTER, PHOTORESISTS, ALKALI RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA THRB 2506/4885LMNA 531/4885AKR1B10 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.