Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342569 | 0.98 | ALDH1A1 (0.61) | THRBTSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL233466 | 0.98 | ALDH1A1 (0.61) | THRBTSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL4970634 | 0.98 | ALDH1A1 (0.61) | THRBTSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL234455 | 0.98 | ALDH1A1 (0.61) | THRBTSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL342699 | 0.98 | ALDH1A1 (0.61) | THRBTSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL146669 | 0.95 | THRB (0.63) | THRBTSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL27929355 | 0.92 | THRB (0.59) | THRBTSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL29315889 | 0.91 | THRB (0.55) | THRBTSHRALDH1A1CYP3A4LMNA | |
| Formic Acid SCHEMBL28238298 | 0.90 | THRB (0.58) | THRBTSHRALDH1A1CYP3A4LMNA | |
| Acetic Acid SCHEMBL28013203 | 0.90 | THRB (0.58) | THRBTSHRALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| CN-115298573-B | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2024-09-06 | — | — | CN | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-4263513-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-10-25 | — | — | EP | claimed |
| EP-1002244-A1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999053348-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS PREPARED USING A POST-POLYMERIZATION CROSS-LINKING METHOD | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| WO-1999052570-A1 | INTRAOCULAR LENS COATING COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| WO-1999052571-A1 | BICOMPOSITE INTRAOCULAR LENS AND METHOD FOR ITS PREPARATION | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| US-5922821-A | A HIGH REFRACTIVE INDEX COPOLYMERS CAN BE USED TO FORM A FLEXIBLE INTRAOCULAR LENS, CAPABLE OF BEING ROLLED OR FOLDED FOR INSERTION THROUGH A SMALL INCISION | ALCON LABORATORIES, INC. (US) | 1999-07-13 | — | — | US | claimed |
| US-5891931-A | CONTAINING A CURABLE ACRYLATED RESIN POLYMER | ALCON LABORATORIES, INC. (US) | 1999-04-06 | — | — | US | claimed |
| WO-1999008136-A1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007756-A1 | OPHTHALMIC LENS POLYMERS | ALCON LABORATORIES, INC. (US) | 1999-02-18 | — | — | WO | claimed |
| US-4139391-A | AN UNSATURATED COMPOUND, A PHOTOINITIATOR AND AN ACRYLIC OR METHACRYLIC ACID COPOLYMER WITH AN ACRYLIC OR METHACRYLIC ESTER, PHOTORESISTS, ALKALI RESISTANCE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-02-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | THRB 2506/4885TSHR 1437/4885ALDH1A1 1323/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | THRB 4655/4885TSHR 4604/4885ALDH1A1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.