Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LOX | P28300 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337378 | 0.88 | LTA4H (0.48) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL16404625 | 0.78 | CNR1 (0.49) | LOXL2NPC1RAB9ALOXMAPT | |
| SCHEMBL30461696 | 0.77 | LOXL2 (0.57) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL631841 | 0.77 | LOXL2 (0.62) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9932200 | 0.77 | LOXL2 (0.57) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL1697728 | 0.77 | LOXL2 (0.57) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8285845 | 0.77 | LOXL2 (0.57) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL17413774 | 0.77 | LOXL2 (0.57) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL28350627 | 0.76 | LOXL2 (0.56) | LOXL2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| Benzene SCHEMBL27860902 | 0.76 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746349-B | Preparation method of m-difluoroalkylphenoxypyridine compound | 安阳师范学院 | 2021-02-09 | — | — | CN | disclosed |
| CN-110746349-A | Preparation method of m-difluoroalkylphenoxypyridine compound | 安阳师范学院 | 2020-02-04 | — | — | CN | disclosed |