SCHEMBL23337378

SCHEMBL23337378

Oc1ccc(Oc2cc(-c3ccccc3)ccn2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.48
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
LOXL2 Q9Y4K0 5/20 0.46
LOX P28300 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C19 P33261 2/20 0.45
NPC1 O15118 1/20 0.45
CYP2C9 P11712 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MMP3 P08254 1/20 0.44
BCL2L1 Q07817 1/20 0.44
ESR1 P03372 4/20 0.43
ESR2 Q92731 3/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PLAU P00749 1/20 0.41
LMNA P02545 1/20 0.40
PTGS1 P23219 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28354523 0.88 LOXL2 (0.57) LTA4HLOXL2LOXCYP1A2CYP2C19
SCHEMBL2906026 0.80 ESR2 (0.48) LTA4HNR1H2BAXLOXL2NPC1
SCHEMBL2904468 0.78 MEN1 (0.54) LTA4HNR1H2BAXLOXL2LOX
SCHEMBL5686657 0.75 LTA4H (0.54) LTA4HNR1H2BAXCYP1A2CYP2C19
SCHEMBL5686902 0.75 DRD1 (0.50) LTA4HNR1H2BAXLOXL2ESR1
SCHEMBL4320112 0.74 LTA4H (0.77) LTA4HNR1H2BAXCYP1A2CYP2C19
SCHEMBL25960632 0.74 LTA4H (0.77) LTA4HNR1H2BAXCYP1A2CYP2C19
SCHEMBL2905557 0.74 ESR2 (0.48) LTA4HNR1H2BAXCYP1A2CYP2C19
SCHEMBL7035776 0.74 LTA4H (0.69) LTA4HNR1H2BAXMMP3BCL2L1
SCHEMBL11426529 0.73 LTA4H (0.82) LTA4HNR1H2BAXMMP3BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210130382-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210130382-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME DDT, ORC3, PPOX LTA4H 1479/4885NR1H2 2682/4885BAX 4621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.