Dimethylformamide

Dimethylformamide

SCHEMBL28355233

CN(C)C=O.COCCOCCOc1c(C)cccc1C

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 4/20 0.47
DRD2 P14416 1/20 0.40
HTR2A P28223 1/20 0.40
SCN8A Q9UQD0 9/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 1/20 0.38
HTR1A P08908 1/20 0.36
ADRA1D P25100 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17668299 0.87 ALDH1A1 (0.57) ALDH1A1KDM4EDRD2HTR2ASCN8A
SCHEMBL20102193 0.78 KDM4E (0.49) ALDH1A1KDM4EDRD2HTR2ASCN8A
Dimethylformamide SCHEMBL28253639 0.76 TSHR (0.47)
Dimethylformamide SCHEMBL6746432 0.76 TSHR (0.47)
Dimethylformamide SCHEMBL7942578 0.76 TSHR (0.47)
SCHEMBL19456538 0.73 ALDH1A1 (0.57) ALDH1A1KDM4EDRD2HTR2ASCN8A
SCHEMBL28042959 0.73 ALDH1A1 (0.53) ALDH1A1KDM4EHTR2ASCN8ASMN1; SMN2
SCHEMBL14929343 0.71 KDM4E (0.39) ALDH1A1KDM4EDRD2HTR2AMAPT
SCHEMBL14929348 0.71 KDM4E (0.39) ALDH1A1KDM4EDRD2HTR2AMAPT
SCHEMBL14929200 0.71 KDM4E (0.39) ALDH1A1KDM4EDRD2HTR2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105511228-B Photoresist compositions and related methods of forming electronic devices 罗门哈斯电子材料有限责任公司 2020-01-14 CN disclosed