SCHEMBL28355348

SCHEMBL28355348

CCC[Se]CC(N)C(O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FDPS P14324 14/20 0.41
LAP3 P28838 2/20 0.38
GGPS1 O95749 5/20 0.33
METAP1 P53582 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28358931 0.79 FDPS (0.41) FDPSLAP3
SCHEMBL28358789 0.76 FDPS (0.32) FDPS
SCHEMBL6665925 0.76 FDPS (0.50) FDPSLAP3GGPS1METAP1
SCHEMBL6132043 0.76 LAP3 (0.46) FDPSLAP3GGPS1METAP1
SCHEMBL5489929 0.76 LAP3 (0.46) FDPSLAP3GGPS1METAP1
SCHEMBL5262879 0.73 FDPS (0.61) FDPSLAP3GGPS1
SCHEMBL28358933 0.72 FDPS (0.38) FDPSLAP3METAP1
SCHEMBL8591903 0.70 FDPS (0.68) FDPSLAP3GGPS1
SCHEMBL5054803 0.69 FDPS (0.41) FDPSLAP3GGPS1
SCHEMBL5054818 0.69 ANPEP (0.44) FDPSLAP3GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106083925-B Diphosphonic acid compound and preparation method and application thereof 成都云克药业有限责任公司 2019-12-31 CN disclosed