Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.61 |
| ▸ | LAP3 | P28838 | 2/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591903 | 0.92 | FDPS (0.68) | FDPSLAP3GGPS1S1PR2S1PR1 | |
| SCHEMBL6665925 | 0.88 | FDPS (0.50) | FDPSLAP3GGPS1 | |
| SCHEMBL6132043 | 0.79 | LAP3 (0.46) | FDPSLAP3GGPS1 | |
| SCHEMBL5489929 | 0.79 | LAP3 (0.46) | FDPSLAP3GGPS1 | |
| SCHEMBL28358933 | 0.74 | FDPS (0.38) | FDPSLAP3 | |
| SCHEMBL16005037 | 0.73 | OPRM1 (0.40) | FDPSLAP3 | |
| SCHEMBL28355348 | 0.73 | FDPS (0.41) | FDPSLAP3GGPS1 | |
| SCHEMBL11040827 | 0.73 | LAP3 (0.56) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL15755365 | 0.72 | CA2 (0.41) | FDPSLAP3 | |
| SCHEMBL5054803 | 0.72 | FDPS (0.41) | FDPSLAP3GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411087-B2 | Process for preparation of bisphosphonic acid compounds | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2008-08-12 | — | — | US | disclosed |
| EP-1817297-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | Pfizer Products Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056854-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20020061866-A1 | Pharmaceutical compositions comprising in combination a bisphosphonate and a matrix metalloproteinase inhibitor | BATAILLE FRAN CCEDIL OIS-REGIS (FR) | 2002-05-23 | — | — | US | disclosed |