Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352595 | 0.90 | RAB9A (0.51) | ALDH1A1POLBF2RL1GAAKMT2A | |
| SCHEMBL28352798 | 0.88 | ALDH1A1 (0.47) | ALDH1A1POLBF2RL1GAAFFAR1 | |
| SCHEMBL28356497 | 0.85 | RAB9A (0.51) | ALDH1A1POLBF2RL1GAAKMT2A | |
| SCHEMBL28882500 | 0.81 | ALDH1A1 (0.58) | ALDH1A1POLBF2RL1GAAFFAR1 | |
| SCHEMBL30509769 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2A | |
| SCHEMBL28356109 | 0.78 | ALDH1A1 (0.58) | ALDH1A1POLBF2RL1GAAFFAR1 | |
| SCHEMBL19891526 | 0.77 | ALDH1A1 (0.63) | ALDH1A1POLBF2RL1GAAKMT2A | |
| SCHEMBL19884358 | 0.76 | ALDH1A1 (0.56) | ALDH1A1POLBF2RL1GAAKMT2A | |
| SCHEMBL11904840 | 0.75 | CTSB (0.54) | ALDH1A1GAAKMT2A | |
| SCHEMBL19884359 | 0.74 | ALDH1A1 (0.53) | ALDH1A1POLBF2RL1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770209-B | Novel 5-hydroxypyridine compounds useful as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2023-06-30 | — | — | CN | disclosed |
| CN-110770209-A | Novel 5-hydroxypyridines as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2020-02-07 | — | — | CN | disclosed |