SCHEMBL28356795

SCHEMBL28356795

O=C(OC(=O)C(c1ccccc1)C(F)(F)F)C(c1ccccc1)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
KMT2A Q03164 1/20 0.42
CYP2D6 P10635 2/20 0.40
SRC P12931 2/20 0.40
CYP1A2 P05177 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 2/20 0.39
MAPK1 P28482 1/20 0.39
CES1 P23141 2/20 0.38
CES2 O00748 1/20 0.38
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
ACP3 P15309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28356796 0.89 L3MBTL1 (0.46) L3MBTL1ATMKMT2ACYP2D6SRC
SCHEMBL27485280 0.88 MAPK1 (0.43) L3MBTL1ATMKMT2ALMNAMAPK1
SCHEMBL9063308 0.85 L3MBTL1 (0.45) L3MBTL1ATMKMT2ACYP2D6SRC
SCHEMBL26598414 0.85 KMT2A (0.58) L3MBTL1ATMKMT2ALMNA
SCHEMBL8692417 0.83 L3MBTL1 (0.70) L3MBTL1ATMKMT2ACYP2D6SRC
SCHEMBL7690988 0.82 L3MBTL1 (0.46) L3MBTL1ATMKMT2ALMNA
SCHEMBL7930466 0.82 MMP8 (0.51) L3MBTL1ATMKMT2ASMN1; SMN2NPSR1
SCHEMBL7955519 0.81 SRC (0.50) L3MBTL1ATMCYP2D6SRCLMNA
SCHEMBL28044484 0.81 CYP2D6 (0.44) L3MBTL1ATMCYP2D6SRCLMNA
SCHEMBL195532 0.81 SRC (0.50) L3MBTL1ATMCYP2D6SRCLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354830-A Process for the preparation of functionalized fluorinated monomers, fluorinated monomers and compositions for the preparation thereof 埃特纳科技有限公司 2023-06-30 CN disclosed
CN-110770271-B Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2023-04-18 CN disclosed
CN-110770271-A Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2020-02-07 CN disclosed