Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28356795 | 0.85 | L3MBTL1 (0.47) | L3MBTL1ATMLMNAMAPK1KMT2A | |
| SCHEMBL7930466 | 0.82 | MMP8 (0.51) | L3MBTL1ATMKMT2ATDP1SMN1; SMN2 | |
| SCHEMBL26598414 | 0.81 | KMT2A (0.58) | L3MBTL1ATMLMNAKMT2A | |
| SCHEMBL3682260 | 0.81 | SRC (0.50) | L3MBTL1ATMLMNAMAPK1KMT2A | |
| SCHEMBL8692417 | 0.80 | L3MBTL1 (0.70) | L3MBTL1ATMKMT2ATDP1CYP2D6 | |
| SCHEMBL14382169 | 0.80 | LMNA (0.49) | L3MBTL1ATMLMNAKMT2ACYP2D6 | |
| SCHEMBL6236555 | 0.79 | LMNA (0.57) | L3MBTL1ATMLMNAMAPK1KMT2A | |
| SCHEMBL7690988 | 0.79 | L3MBTL1 (0.46) | L3MBTL1ATMLMNAKMT2A | |
| SCHEMBL28356796 | 0.79 | L3MBTL1 (0.46) | L3MBTL1ATMKMT2ACYP2D6SRC | |
| SCHEMBL7955519 | 0.78 | SRC (0.50) | L3MBTL1ATMLMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8333303-A | — | — | None | — | — | JP | disclosed |
| CN-109942406-A | A kind of preparation method of 2- (3,5- bis--trifluoromethyl-phenyl) -2- rnethyl-propanoic acid | 上海天慈国际药业有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-104109121-A | N'-aryl acetyl o-pyridine hydrazide derivatives, and preparation methods, pharmaceutical composition and application thereof | INST MATERIA MEDICA CAMS | 2014-10-22 | — | — | CN | disclosed |
| JP-H08333303-A | ALPHA, ALPHA-BIS(TRIFLUOROMETHYL) ARYLACETIC ESTER AND ITS PRODUCTION | NIPPON MEKTRON LTD | 1996-12-17 | — | — | JP | disclosed |