SCHEMBL28357232

SCHEMBL28357232

O=C1CC(c2ccccc2)(c2ccccc2)C(=O)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
POLB P06746 1/20 0.44
PKM P14618 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
CASP1 P29466 1/20 0.40
CA7 P43166 1/20 0.40
RECQL P46063 1/20 0.40
BACE1 P56817 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3089520 0.80 NPSR1 (0.51) MAPTGAARAB9ASMN1; SMN2KMT2A
SCHEMBL181563 0.80 CFTR (0.48) MAPTGAARAB9ASMN1; SMN2KMT2A
SCHEMBL30074263 0.80 CFTR (0.48) MAPTGAARAB9ASMN1; SMN2KMT2A
SCHEMBL7760631 0.72 MEN1 (0.47) MAPTGAARAB9ASMN1; SMN2KMT2A
SCHEMBL6552460 0.72 ESR1 (0.51) MAPTGAASMN1; SMN2KMT2AMEN1
SCHEMBL6550908 0.72 CFTR (0.41) MAPTGAASMN1; SMN2KMT2AMEN1
SCHEMBL2724212 0.71 ALDH1A1 (0.54) MAPTGAARAB9ASMN1; SMN2KMT2A
SCHEMBL29244104 0.71 KMT2A (0.46) MAPTGAARAB9ASMN1; SMN2KMT2A
SCHEMBL28680129 0.71 POLB (0.54) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL15657386 0.71 CFTR (0.45) MAPTGAAKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106575078-B Photosensitive composition, cured film and method for producing the same, touch panel and display device thereof, liquid crystal display device, and organic EL display device 富士胶片株式会社 2020-02-21 CN disclosed