Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TYMS | P04818 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074263 | 0.90 | CFTR (0.48) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL181563 | 0.90 | CFTR (0.48) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL6550908 | 0.84 | CFTR (0.41) | ESR1ESR2MEN1LMNAKMT2A | |
| Propionic Acid SCHEMBL4796324 | 0.81 | PKM (0.41) | LMNAKMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL6550929 | 0.80 | MAPT (0.46) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL28606394 | 0.80 | MDM2 (0.40) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL28609498 | 0.80 | PGR (0.38) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL10617456 | 0.77 | ESR1 (0.46) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL14462993 | 0.77 | S100A4 (0.42) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL23786164 | 0.74 | MAPT (0.40) | ESR1ESR2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047411-B1 | SUBSTITUTED DIPHENYL INDANONE, INDANE AND INDOLE COMPOUNDS AND ANALOGUES THEREOF USEFUL FOR THE TREATMENT OR PREVENTION OF DISEASES CHARACTERIZED BY ABNORMAL CELL PROLIFERATION | HARVARD COLLEGE (US) | 2004-02-11 | — | — | EP | disclosed |