Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920984 | 0.85 | MAPT (0.43) | NPSR1L3MBTL1LMNAHTTGAA | |
| SCHEMBL28357232 | 0.80 | MAPT (0.44) | NPSR1L3MBTL1LMNAHTTCFTR | |
| SCHEMBL14938940 | 0.77 | NPSR1 (0.49) | NPSR1L3MBTL1LMNAHTTCFTR | |
| SCHEMBL9641039 | 0.77 | LMNA (0.49) | NPSR1L3MBTL1LMNAHTTCFTR | |
| SCHEMBL31722857 | 0.72 | PDK2 (0.43) | NPSR1L3MBTL1LMNAHTTGAA | |
| SCHEMBL3134200 | 0.72 | NPSR1 (0.44) | NPSR1L3MBTL1LMNAHTTCFTR | |
| SCHEMBL4459204 | 0.71 | NPSR1 (0.50) | NPSR1L3MBTL1LMNAHTTMAOA | |
| SCHEMBL3994729 | 0.71 | L3MBTL1 (0.50) | NPSR1L3MBTL1LMNAHTTMAOA | |
| SCHEMBL11500029 | 0.71 | SIGMAR1 (0.51) | NPSR1L3MBTL1LMNAHTTMAOA | |
| SCHEMBL4463201 | 0.71 | NPSR1 (0.50) | NPSR1L3MBTL1LMNAHTTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890881-B | Method for simply synthesizing allyl dicarbonyl compound | 南阳师范学院 | 2023-06-02 | — | — | CN | disclosed |
| US-20220047557-A1 | TREATMENT OF CARDIAC DISORDERS BY BLOCKING SK4 POTASSIUM CHANNEL | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-02-17 | — | — | US | disclosed |
| US-11166940-B2 | Treatment of cardiac disorders by blocking SK4 potassium channel | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2021-11-09 | — | — | US | disclosed |
| CN-108697081-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20180177764-A1 | TREATMENT OF CARDIAC DISORDERS BY BLOCKING SK4 POTASSIUM CHANNEL | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2018-06-28 | — | — | US | disclosed |
| US-9691999-B2 | Photoelectric conversion device vapor deposition material, photoelectric conversion device, sensor, and imaging device | FUJIFILM CORPORATION (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20140138522-A1 | PHOTOELECTRIC CONVERSION DEVICE VAPOR DEPOSITION MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, SENSOR, AND IMAGING DEVICE | FUJIFILM CORPORATION (JP) | 2014-05-22 | — | — | US | disclosed |
| WO-2013015441-A1 | PHOTOELECTRIC CONVERSION DEVICE VAPOR DEPOSITION MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, SENSOR, AND IMAGE PICKUP DEVICE | FUJIFILM CORPORATION (JP) | 2013-01-31 | — | — | WO | disclosed |
| WO-2010109008-A1 | PRODRUGS OF SUBSTITUTED 3-(4-HYDROXYPHENYL)-INDOLIN-2-ONES | TOPOTARGET A/S (DK) | 2010-09-30 | — | — | WO | disclosed |
| US-20100227863-A1 | SUBSTITUTED 3-(4-HYDROXYPHENYL)-INDOLIN-2-ONE COMPOUNDS | TOPOTARGET A/S (DK) | 2010-09-09 | — | — | US | disclosed |
| US-7342038-B2 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation | PRESIDENT AND FELLOW OF HARVARD COLLEGE (US) | 2008-03-11 | — | — | US | disclosed |
| US-20070299102-A1 | Diphenyl Ox-Indol-2-One Compounds and Their Use in the Treatment of Cancer | TOPO TARGET A/S (DK) | 2007-12-27 | — | — | US | disclosed |
| EP-1734951-A2 | DIPHENYL-INDOL-2-ON COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | TopoTarget A/S (DK) | 2006-12-27 | — | — | EP | disclosed |
| CN-1688288-A | Preparation of submicron sized particles with polymorph control and new polymorph of itraconazole | BAXTER INT (US) | 2005-10-26 | — | — | CN | disclosed |
| WO-2005097107-A2 | DIPHENYL - INDOL-2-ON COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | TOPOTARGET A/S (DK) | 2005-10-20 | — | — | WO | disclosed |
| US-20040242563-A1 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation | CHILDREN'S MEDICAL CENTER CORPORATION | 2004-12-02 | — | — | US | disclosed |
| US-6800658-B2 | A POTENT AND SAFE INHIBITORS OF MAMMALIAN CELL PROLIFERATION FOR TREATING OR PREVENTING CANCER, BLOOD VESSEL PROLIFERATIVE DISORDERS, FIBROTIC DISORDERS AND ARTERIOSCLEROTIC CONDITIONS | CHILDREN'S MEDICAL CENTER CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-20020198188-A1 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation | CHILDREN'S MEDICAL CENTER CORPORATION | 2002-12-26 | — | — | US | disclosed |
| US-20020128256-A1 | Methods for the treatment or prevention of inflammatory diseases characterized by abnormal cell proliferation | BRUGNARA CARLO (US) | 2002-09-12 | — | — | US | disclosed |
| CN-1306422-A | Substituted diphenyl indanone, indane and indole compounds and analogs thereof for the treatment or prevention of diseases characterized by abnormal cell proliferation | HARVARD COLLEGE (US) | 2001-08-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128256-A1 | Methods for the treatment or prevention of inflammatory diseases characterized by abnormal cell proliferation | KCNN3, KCNN2, KCNN1 | NPSR1 3140/4885L3MBTL1 3719/4885LMNA 1063/4885 |
| US-11166940-B2 | Treatment of cardiac disorders by blocking SK4 potassium channel | KCNN3, KCNK4, KCNN1 | NPSR1 911/4885L3MBTL1 923/4885LMNA 1661/4885 |
| US-20220047557-A1 | TREATMENT OF CARDIAC DISORDERS BY BLOCKING SK4 POTASSIUM CHANNEL | KCNN3, KCNK4, KCNN1 | NPSR1 911/4885L3MBTL1 923/4885LMNA 1661/4885 |
| US-20070299102-A1 | Diphenyl Ox-Indol-2-One Compounds and Their Use in the Treatment of Cancer | MTOR, RICTOR, CDK4 | NPSR1 3513/4885L3MBTL1 464/4885LMNA 3104/4885 |
| US-20040242563-A1 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation | IDO1, ING2, MKI67 | NPSR1 2537/4885L3MBTL1 742/4885LMNA 2365/4885 |
| US-20100227863-A1 | SUBSTITUTED 3-(4-HYDROXYPHENYL)-INDOLIN-2-ONE COMPOUNDS | TPH2, TPH1, HTR2C | NPSR1 1252/4885L3MBTL1 2191/4885LMNA 2104/4885 |
| US-20020198188-A1 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation | IDO1, IDO2, ING2 | NPSR1 2482/4885L3MBTL1 714/4885LMNA 2296/4885 |
| US-20180177764-A1 | TREATMENT OF CARDIAC DISORDERS BY BLOCKING SK4 POTASSIUM CHANNEL | KCNN3, KCNK4, KCNN1 | NPSR1 911/4885L3MBTL1 923/4885LMNA 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.