SCHEMBL28358532

SCHEMBL28358532

C=CCOC(=O)C(CC1CCCCC1)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
CASP1 P29466 1/20 0.39
NPSR1 Q6W5P4 1/20 0.33
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
LMNA P02545 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRM2 Q14416 1/20 0.31
GRM3 Q14832 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28558880 0.74 ALDH1A1 (0.43) ALDH1A1GAACASP1NPSR1NPC1
SCHEMBL8330411 0.72 ALDH1A1 (0.38) ALDH1A1GAACASP1NPSR1NPC1
SCHEMBL19629 0.71 CASP1 (0.60) ALDH1A1GAACASP1MAPTLMNA
SCHEMBL1226275 0.71 THRA (0.38) ALDH1A1GAACASP1MAPTRAB9A
SCHEMBL2535863 0.71 GRM2 (0.45) LMNAGRM2GRM3EPHX1
SCHEMBL28564478 0.71 CHRM2 (0.39) ALDH1A1GAACASP1NPSR1LMNA
SCHEMBL21059 0.70 ALDH1A1 (0.51) ALDH1A1GAACASP1NPSR1NPC1
SCHEMBL28010184 0.70 ALDH1A1 (0.48) ALDH1A1GAACASP1NPSR1NPC1
SCHEMBL8330413 0.70 CASP1 (0.37) ALDH1A1GAACASP1NPSR1NPC1
SCHEMBL28564488 0.70 TSHR (0.39) ALDH1A1GAACASP1NPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110819451-A Unsaturated lactones as odorants 西姆莱斯股份公司 2020-02-21 CN disclosed