SCHEMBL2836987

SCHEMBL2836987

Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(-c3nnn(CC4CC4)n3)c2)c1=O

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
MMP13 P45452 7/20 0.34
POLB P06746 2/20 0.33
KMT2A Q03164 2/20 0.33
QPCT Q16769 1/20 0.33
CRHR1 P34998 3/20 0.32
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KCNJ6 P48051 1/20 0.31
KCNJ5 P48544 1/20 0.31
KCNJ3 P48549 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2834363 0.88 BRD9 (0.34) KMT2ANPC1HPGDRAB9AL3MBTL1
SCHEMBL2841614 0.85 KDM4E (0.32) KMT2ANPC1HPGDRAB9AL3MBTL1
SCHEMBL2834947 0.85 DDX3X (0.36) KMT2ANPC1HPGDRAB9AL3MBTL1
SCHEMBL2833844 0.85 NPC1 (0.39) POLBKMT2ANPC1HPGDRAB9A
SCHEMBL2837070 0.85 ESR1 (0.40) MMP13KMT2ANPC1HPGDRAB9A
SCHEMBL2834359 0.85 NPC1 (0.39) POLBKMT2ANPC1HPGDRAB9A
SCHEMBL2836109 0.85 KMT2A (0.40) MMP13KMT2AQPCTNPC1HPGD
SCHEMBL2835883 0.85 NPC1 (0.32) NPC1HPGDRAB9AL3MBTL1
SCHEMBL1573784 0.84 NPC1 (0.39) POLBKMT2ANPC1HPGDRAB9A
SCHEMBL2842393 0.84 XPO1 (0.32) POLBNPC1HPGDRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754880-B2 Uracils having a herbicidal activity ISAGRO RICERCA S.R.L. (IT) 2010-07-13 US claimed
US-20060025591-A1 New uracils having a herbicidal activity ISEM S.R.L. (IT) 2006-02-02 US claimed
US-7754880-B2 Uracils having a herbicidal activity ISAGRO RICERCA S.R.L. (IT) 2010-07-13 US disclosed
US-20060025591-A1 New uracils having a herbicidal activity ISEM S.R.L. (IT) 2006-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025591-A1 New uracils having a herbicidal activity UNG, DDT, UMPS CNR1 3640/4885CNR2 3677/4885MMP13 4336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.