Biphenyl

Biphenyl

SCHEMBL2835937

O=C(O)c1cccc(F)c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.68
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
PARP1 P09874 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
HDAC1 Q13547 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
KCNK3 O14649 1/20 0.53
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
NPC1 O15118 1/20 0.51
HPGD P15428 1/20 0.51
RAB9A P51151 1/20 0.51
NR4A2 P43354 1/20 0.51
MAP2K4 P45985 1/20 0.51
DAO P14920 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13950378 0.92 CES2 (0.71) KMOCES2CES1PARP1L3MBTL1
SCHEMBL29665004 0.92 CES2 (0.71) KMOCES2CES1PARP1L3MBTL1
SCHEMBL28396 0.92 CES2 (0.71) KMOCES2CES1PARP1L3MBTL1
Hydrochloric Acid SCHEMBL30596526 0.90 CES2 (0.68) KMOCES2CES1PARP1L3MBTL1
Hydrochloric Acid SCHEMBL5777634 0.90 CES2 (0.68) KMOCES2CES1PARP1L3MBTL1
Lithium SCHEMBL30901907 0.90 CES2 (0.68) KMOCES2CES1PARP1L3MBTL1
SCHEMBL11459100 0.90 CES2 (0.68) KMOCES2CES1PARP1L3MBTL1
SCHEMBL28208655 0.90 CES2 (0.68) KMOCES2CES1PARP1L3MBTL1
SCHEMBL121809 0.88 KMO (0.68) KMOCES2CES1PARP1NR4A2
Water SCHEMBL10357175 0.88 CES2 (0.65) KMOCES2CES1PARP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263268-B2 Ester compound, and non-aqueous electrolyte solution and lithium secondary battery each using the ester compound UBE INDUSTRIES, LTD. (JP) 2012-09-11 US disclosed
EP-2108640-B1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES (JP) 2012-07-25 EP disclosed
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES, LTD. (JP) 2010-05-13 US disclosed
EP-2108640-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND Ube Industries, Ltd. (JP) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND CEL, LAGE3, PEF1 KMO 3136/4885CES2 87/4885CES1 994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.