Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.48 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807894 | 0.73 | ALDH1A1 (0.53) | HRH1HRH4ALDH1A1HPGDNPSR1 | |
| SCHEMBL2809937 | 0.71 | HRH1 (0.44) | HRH1HRH4SRCMEN1KMT2A | |
| SCHEMBL2831681 | 0.70 | SIGMAR1 (0.53) | HRH1HRH4ALDH1A1NPSR1SRC | |
| SCHEMBL2786942 | 0.69 | HRH4 (0.54) | HRH4ALDH1A1HPGDNPSR1SRC | |
| SCHEMBL829177 | 0.67 | AR (0.65) | HTR1AADRA1AADRA1BALDH1A1NPSR1 | |
| SCHEMBL31388194 | 0.66 | AR (0.62) | HTR1AADRA1AADRA1BALDH1A1NPSR1 | |
| SCHEMBL7528396 | 0.66 | AR (0.62) | HTR1AADRA1AADRA1BALDH1A1NPSR1 | |
| SCHEMBL1660394 | 0.66 | AR (0.62) | HTR1AADRA1AADRA1BALDH1A1NPSR1 | |
| SCHEMBL7524105 | 0.66 | AR (0.62) | HTR1AADRA1AADRA1BALDH1A1NPSR1 | |
| SCHEMBL2814606 | 0.65 | CDK1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |