Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831681 | 0.84 | SIGMAR1 (0.53) | ALDH1A1L3MBTL1KDM4ESIGMAR1MEN1 | |
| SCHEMBL2786942 | 0.79 | HRH4 (0.54) | ALDH1A1KDM4EHPGDLMNAMAPK1 | |
| SCHEMBL2809937 | 0.79 | HRH1 (0.44) | LMNASIGMAR1MEN1KMT2AMAPK1 | |
| SCHEMBL4942177 | 0.75 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1KDM4EHPGDLMNA | |
| SCHEMBL19140386 | 0.74 | SIGMAR1 (0.42) | ALDH1A1L3MBTL1KDM4EHPGDLMNA | |
| SCHEMBL2835938 | 0.73 | SLC2A1 (0.48) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL2814606 | 0.71 | CDK1 (0.42) | ALDH1A1SIGMAR1HTR2C | |
| SCHEMBL2807570 | 0.71 | PIK3CA (0.56) | HTR2C | |
| SCHEMBL2857759 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDLMNASIGMAR1 | |
| SCHEMBL11979819 | 0.71 | SIGMAR1 (0.51) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |