Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.87 |
| ▸ | HPGD | P15428 | 3/20 | 0.87 |
| ▸ | MEN1 | O00255 | 2/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.87 |
| ▸ | IKBKB | O14920 | 3/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062225 | 0.93 | GAA (1.00) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL611912 | 0.82 | GAA (0.73) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3510525 | 0.81 | IKBKB (1.00) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL15960089 | 0.80 | GAA (0.75) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4057174 | 0.79 | ADORA1 (1.00) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28359880 | 0.78 | GAA (0.70) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7057166 | 0.76 | GAA (0.75) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1563613 | 0.76 | GAA (1.00) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7058046 | 0.75 | GAA (0.73) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4212681 | 0.75 | ALDH1A1 (0.67) | GAAALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724137-B | Thiophene derivative and preparation method and application thereof | 广东工业大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-110724137-A | Thiophene derivative and preparation method and application thereof | 广东工业大学 | 2020-01-24 | — | — | CN | disclosed |