Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360723 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL28357008 | 0.80 | FSCN1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL28360698 | 0.76 | TSHR (0.40) | KDM4EALDH1A1 | |
| SCHEMBL28360711 | 0.75 | HTT (0.44) | KDM4EALDH1A1MAPT | |
| SCHEMBL28360720 | 0.72 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL28883288 | 0.71 | SMN1; SMN2 (0.39) | TTR | |
| SCHEMBL28356849 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL4300629 | 0.68 | TTR (0.47) | TTRALBPGRKDM4EALDH1A1 | |
| SCHEMBL13283750 | 0.67 | MAP2K1 (0.51) | TTRALBMAP2K1 | |
| SCHEMBL2521954 | 0.67 | TTR (0.40) | TTRALBMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804008-A | 1, 3-disubstituted indoline derivative and preparation method thereof | 陕西科技大学 | 2020-02-18 | — | — | CN | disclosed |