Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360720 | 0.84 | KDM4E (0.36) | SMN1; SMN2TSPOMEN1KMT2ATSHR | |
| SCHEMBL28356849 | 0.83 | ALDH1A1 (0.40) | TSPOMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL28360698 | 0.79 | TSHR (0.40) | SMN1; SMN2TSPOMEN1KMT2ACYP3A4 | |
| SCHEMBL28360723 | 0.75 | KDM4E (0.36) | SMN1; SMN2TSPOMEN1KMT2ATSHR | |
| SCHEMBL28357008 | 0.74 | FSCN1 (0.42) | TSPOMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL28360665 | 0.71 | TTR (0.36) | TTR | |
| SCHEMBL28360711 | 0.70 | HTT (0.44) | MEN1KMT2ALSSCYP3A4LMNA | |
| SCHEMBL27465873 | 0.69 | SMN1; SMN2 (0.33) | SMN1; SMN2KMT2ATSHR | |
| SCHEMBL27465872 | 0.69 | SMN1; SMN2 (0.36) | SMN1; SMN2LSSTSHR | |
| SCHEMBL14691956 | 0.67 | C5AR1 (0.40) | SMN1; SMN2TSPOMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804008-A | 1, 3-disubstituted indoline derivative and preparation method thereof | 陕西科技大学 | 2020-02-18 | — | — | CN | disclosed |