Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TSPO | P30536 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360723 | 0.88 | KDM4E (0.36) | KDM4EALDH1A1TDP1C5AR1SMN1; SMN2 | |
| SCHEMBL28883288 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1TSPOTSHR | |
| SCHEMBL28356849 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TDP1HPGDKMT2AMEN1 | |
| SCHEMBL28360698 | 0.80 | TSHR (0.40) | KDM4EALDH1A1C5AR1SMN1; SMN2KMT2A | |
| SCHEMBL28357008 | 0.75 | FSCN1 (0.42) | ALDH1A1TDP1HPGDKMT2AMEN1 | |
| SCHEMBL28360665 | 0.72 | TTR (0.36) | KDM4EALDH1A1 | |
| SCHEMBL28360711 | 0.71 | HTT (0.44) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL5242219 | 0.69 | KDM4E (0.33) | KDM4EALDH1A1TDP1SMN1; SMN2HPGD | |
| SCHEMBL14691956 | 0.68 | C5AR1 (0.40) | KDM4EALDH1A1C5AR1SMN1; SMN2KMT2A | |
| SCHEMBL28500415 | 0.68 | SCN2A (0.32) | ALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804008-A | 1, 3-disubstituted indoline derivative and preparation method thereof | 陕西科技大学 | 2020-02-18 | — | — | CN | disclosed |