Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | C1R | P00736 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.30 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360698 | 0.83 | TSHR (0.40) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL28356782 | 0.83 | ALDH1A1 (0.42) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7497690 | 0.77 | ALDH1A1 (0.49) | CYP3A4ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL19155104 | 0.69 | TSPO (0.51) | LMNAALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL14587285 | 0.68 | KDM4E (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL27661498 | 0.67 | GAA (0.39) | LMNAALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL11083920 | 0.67 | GAA (0.39) | LMNAALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL28948542 | 0.67 | TSHR (0.40) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL29009675 | 0.66 | TP53 (0.41) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL26756570 | 0.65 | APP (0.38) | ALDH1A1TSHRGAAC1RCRY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804008-A | 1, 3-disubstituted indoline derivative and preparation method thereof | 陕西科技大学 | 2020-02-18 | — | — | CN | disclosed |