Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6416782 | 0.83 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL219412 | 0.83 | ALDH1A1 (0.40) | MEN1KMT2A | |
| SCHEMBL1225091 | 0.81 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL7173632 | 0.81 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL8395626 | 0.81 | MEN1 (0.38) | MEN1KMT2A | |
| SCHEMBL5399496 | 0.79 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL12395034 | 0.79 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL3839821 | 0.79 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL3449192 | 0.78 | LMNA (0.33) | — | |
| SCHEMBL7180910 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678466-B | Diazanaphthalenes as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-110678466-A | Naphthyridines as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2020-01-10 | — | — | CN | disclosed |