Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.53 |
| ▸ | TFEB | P19484 | 1/20 | 0.53 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357068 | 0.90 | ALDH1A1 (0.55) | KDM4ENPC1MAPTRAB9AMAPK1 | |
| SCHEMBL28356950 | 0.89 | TUBB4A (0.54) | NFE2L2KDM4EMAPTRAB9AMAPK1 | |
| SCHEMBL28356915 | 0.87 | NFE2L2 (0.58) | NFE2L2TFEBLY96KDM4ENPC1 | |
| SCHEMBL28360755 | 0.85 | CA9 (0.49) | KDM4ENPC1MAPTRAB9ANPSR1 | |
| SCHEMBL28360775 | 0.84 | HSD11B1 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28360863 | 0.82 | F3 (0.50) | KDM4ENPC1MAPTRAB9AMAPK1 | |
| SCHEMBL28356945 | 0.82 | CA9 (0.53) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL28357183 | 0.79 | HSD11B1 (0.47) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28756580 | 0.78 | F3 (0.56) | KDM4ENPC1MAPTRAB9ANOD2 | |
| SCHEMBL28356957 | 0.78 | ALDH1A1 (0.46) | KDM4ENPC1MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928176-B | Coumarin-containing 1, 4-pentadiene-3-ketone derivative and preparation method and application thereof | 贵州大学 | 2020-02-18 | — | — | CN | disclosed |