SCHEMBL415882

SCHEMBL415882

Brc1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
RAB9A P51151 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
KDM4E B2RXH2 1/20 0.59
NPC1 O15118 1/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
HPGD P15428 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
SRD5A2 P31213 1/20 0.52
CYP1A2 P05177 3/20 0.49
CYP3A4 P08684 2/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
METAP1 P53582 1/20 0.48
TRPA1 O75762 1/20 0.47
TDP2 O95551 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29780658 1.00 ALDH1A1 (0.59) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
Fluorene SCHEMBL15453329 1.00 ALDH1A1 (0.59) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL29466104 1.00 ALDH1A1 (0.59) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
Ammonia Solution, Strong SCHEMBL665105 0.98 ALDH1A1 (0.57) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL17313627 0.94 SMN1; SMN2 (0.53) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL23542831 0.91 L3MBTL1 (0.56) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL19237245 0.91 L3MBTL1 (0.56) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL1806266 0.91 L3MBTL1 (0.56) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL29376113 0.89 METAP1 (0.57) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL40823 0.89 METAP1 (0.57) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120158212-A Production process of wear-resistant polyurethane coating 佛山市坤瑞建材科技有限公司 2025-06-17 CN claimed
CN-115850313-B Method for preparing 9, 9-dioctyl-2-fluorenylboric acid 中唯炼焦技术国家工程研究中心有限责任公司 2025-03-04 CN claimed
CN-119263958-A Method for preparing 2-bromofluorene by oxidizing and brominating 南京工业大学 2025-01-07 CN claimed
CN-119064498-A Synchronous rapid detection method for 31 halogenated polycyclic aromatic hydrocarbons in complex cooked food matrix 广东工业大学 2024-12-03 CN claimed
CN-118812567-A Nasopharyngeal carcinoma resisting photosensitizer with photothermal and photodynamic effects and preparation method and application thereof 湘南学院 2024-10-22 CN claimed
CN-118359639-A Near infrared two-region small molecule and synthesis and application thereof in biliary tract occlusion 烟台新药创制山东省实验室 2024-07-19 CN claimed
CN-114014744-B Method for preparing 2-bromo-9, 9-dimethylfluorene by catalysis 中唯炼焦技术国家工程研究中心有限责任公司 2024-07-09 CN claimed
CN-115572234-B Fluorescent tracer for horizontal well multistage clustered fracturing and preparation method thereof 西南石油大学 2023-08-18 CN claimed
CN-219209038-U Crystallization device for purifying 2-bromofluorene 许昌圣壹新材料科技有限公司 2023-06-20 CN claimed
CN-218950175-U Automatic feeding device for preparing 2-bromofluorene 许昌圣壹新材料科技有限公司 2023-05-02 CN claimed
CN-101429094-B Process for producing 2, 7-dibromo-9, 9-dialkyl fluorene INST PETROCHEMISTRY HEILONGJIANG ACADEMY OF SCIENCE 2010-08-25 CN claimed
CN-101481292-A Preparation of 2-bromofluorenone PUYANG HUICHENG CHEMICAL CO LT (CN) 2009-07-15 CN claimed
CN-100489006-C Method for preparing poly (9,9 dialkyl fluorene) CHANGCHUN APPLIED CHEMISTRY (CN) 2009-05-20 CN claimed
CN-101429094-A Process for producing 2, 7-dibromo-9, 9-dialkyl fluorene INST OF PETROCHEMISTRY HEILONG (CN) 2009-05-13 CN claimed
CN-100422128-C Oxidation preparation method for 9- fluorenone compound from fluorine compound UNIV SHANXI (CN) 2008-10-01 CN claimed
CN-101225298-A Hole-transporting type blue luminescent material as well as preparation and uses thereof CHINESE ACAD INST CHEMISTRY (CN) 2008-07-23 CN claimed
CN-101092475-A Method for preparing poly (9,9 di alkyl fluorene) CHANGCHUN APPLIED CHEMISTRY (CN) 2007-12-26 CN claimed
CN-101007943-A Pyrrolepyrrolidine-diones-fluorene copolymer electroluminescent material and its preparation method UNIV SOUTH CHINA TECH (CN) 2007-08-01 CN claimed
CN-1962597-A Oxidation preparation method for 9- fluorenone compound from fluorine compound UNIV SHANXI (CN) 2007-05-16 CN claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed