SCHEMBL283612

SCHEMBL283612

Nc1cccc([N+](=O)[O-])c1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
LMNA P02545 2/20 0.50
TSHR P16473 1/20 0.50
GPR35 Q9HC97 2/20 0.48
PDE7A Q13946 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPK1 P28482 1/20 0.45
APEX1 P27695 1/20 0.44
KDM4E B2RXH2 1/20 0.43
CTSD P07339 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11180501 0.98 TDP1 (0.62) TDP1L3MBTL1LMNATSHRGPR35
SCHEMBL1554602 0.86 TDP1 (0.75) TDP1L3MBTL1TSHRGPR35APEX1
SCHEMBL11328396 0.85 TDP1 (0.50) TDP1L3MBTL1LMNATSHRGPR35
SCHEMBL11854765 0.84 MAPK1 (0.60) TDP1L3MBTL1LMNATSHRGPR35
SCHEMBL14701846 0.84 TDP1 (0.49) TDP1L3MBTL1LMNATSHRGPR35
SCHEMBL8477874 0.84 TDP1 (0.53) TDP1L3MBTL1LMNATSHRGPR35
SCHEMBL11644545 0.83 LMNA (0.56) TDP1L3MBTL1LMNATSHRGPR35
Hydrogen Sulfide SCHEMBL28004578 0.82 TDP1 (0.70) TDP1L3MBTL1TSHRGPR35APEX1
SCHEMBL30785354 0.80 TDP1 (0.44) TDP1L3MBTL1LMNATSHRALDH1A1
SCHEMBL11833211 0.80 GPR35 (0.47) TDP1L3MBTL1TSHRGPR35PDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 782 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638583-A Production process of 2-amino-6-nitrobenzoic acid 山东极地医药科技有限公司 2025-03-18 CN claimed
CN-116143635-B Preparation method of 9-dichloromethylene-5-amino-benzonorbornene 江苏七洲绿色科技研究院有限公司 2025-02-25 CN claimed
CN-116143635-A Preparation method of 9-dichloromethylene-5-amino-benzonorbornene 江苏七洲绿色科技研究院有限公司 2023-05-23 CN claimed
CN-111454157-B Preparation method of 3-nitrophenyl alkyne 利民化学有限责任公司 2022-07-22 CN claimed
CN-112028813-A 4-chloro indole compound and preparation method thereof 平顶山学院 2020-12-04 CN claimed
CN-112028811-A 4-iodo-indole compound and preparation method thereof 平顶山学院 2020-12-04 CN claimed
CN-112028812-A 4-bromoindole compound and preparation method thereof 平顶山学院 2020-12-04 CN claimed
CN-111454157-A Preparation method of 3-nitrophenyl alkyne 利民化学有限责任公司 2020-07-28 CN claimed
CN-108003030-B Method and device for continuously preparing 5-nitro-1, 4-dihydro-1, 4-methano-naphthalene in pipelining manner 浙江工业大学 2020-03-31 CN claimed
EP-2349980-B1 Process for preparing 2-amino-6-nitro-benzoic acid PERKINELMER HEALTH SCI INC (US) 2018-09-26 EP claimed
EP-1928838-B1 PROCESS FOR THE PRODUCTION OF AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-10-24 EP claimed
CN-101277938-B Process for producing amides SYNGENTA PARTICIPATIONS AG 2012-01-11 CN claimed
US-7994341-B2 Process for the production of amides SYNGENTA LIMITED (GB) 2011-08-09 US claimed
EP-2349980-A2 METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS PerkinElmer Health Sciences, Inc. (US) 2011-08-03 EP claimed
WO-2010045352-A2 METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS PERKINELMER HEALTH SCIENCES, INC. (US) 2010-04-22 WO claimed
US-20100094046-A1 METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS REVVITY HEALTH SCIENCES, INC. 2010-04-15 US claimed
US-20090163569-A1 PROCESS FOR THE PRODUCTION OF AMIDES SYNGENTA CROP PROTECTION, INC. (US) 2009-06-25 US claimed
CN-101277938-A Process for producing amides SYNGENTA PARTICIPATIONS AG (CH) 2008-10-01 CN claimed
EP-1928838-A1 PROCESS FOR THE PRODUCTION OF AMIDES Syngeta Participations AG (CH) 2008-06-11 EP claimed
WO-2007031323-A1 PROCESS FOR THE PRODUCTION OF AMIDES SYNGENTA PARTICIPATIONS AG. (CH) 2007-03-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094046-A1 METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS AADAT, DDC, DAO TDP1 1815/4885L3MBTL1 1844/4885LMNA 3882/4885
US-20090163569-A1 PROCESS FOR THE PRODUCTION OF AMIDES C5, CFH, C9 TDP1 4754/4885L3MBTL1 2547/4885LMNA 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.