Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17947267 | 0.86 | NPSR1 (0.46) | NPSR1KDM4EGAAHPGDKMT2A | |
| SCHEMBL1922073 | 0.82 | NPSR1 (0.72) | NPSR1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL16481495 | 0.81 | ALDH1A1 (0.49) | NPSR1KDM4EGAAHPGDALDH1A1 | |
| SCHEMBL28216056 | 0.81 | GAA (0.55) | NPSR1KDM4EGAAHPGDALDH1A1 | |
| SCHEMBL20552441 | 0.80 | LMNA (0.47) | NPSR1KDM4EGAAHPGDALDH1A1 | |
| SCHEMBL17947386 | 0.80 | RAB9A (0.50) | NPSR1HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL4188631 | 0.80 | AURKA (0.59) | KDM4EGAAHPGDALDH1A1LRRK2 | |
| SCHEMBL28361136 | 0.80 | KCNK18 (0.49) | KDM4EGAAHPGDALDH1A1LRRK2 | |
| SCHEMBL20552820 | 0.80 | RAPGEF4 (0.48) | KDM4EGAAHPGDALDH1A1LRRK2 | |
| SCHEMBL28364827 | 0.80 | KDM4E (0.55) | NPSR1KDM4EGAAALDH1A1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698399-B | Preparation method of aryl acridine derivative synthesized by palladium catalysis | 温州大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-110698399-A | Aryl acridine derivative synthesized by palladium catalysis and preparation method thereof | 温州大学 | 2020-01-17 | — | — | CN | disclosed |