Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 4/20 | 0.39 |
| ▸ | SELE | P16581 | 4/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519545 | 0.87 | AOC3 (0.39) | ADORA2AKMT2AMAPTMEN1PARP10 | |
| SCHEMBL28173038 | 0.79 | SMN1; SMN2 (0.51) | KMT2AMAPTMEN1 | |
| SCHEMBL28375297 | 0.76 | KMT2A (0.41) | KMT2AMAPTMEN1PARP10FFAR1 | |
| SCHEMBL26093046 | 0.76 | KMT2A (0.41) | KMT2AMAPTMEN1PARP10FFAR1 | |
| SCHEMBL19025180 | 0.76 | ESR1 (0.44) | — | |
| SCHEMBL28941178 | 0.75 | KIF11 (0.34) | ADORA2AKMT2AMAPTMEN1PARP10 | |
| SCHEMBL17784972 | 0.74 | PIK3CD (0.36) | KMT2AMAPTMEN1 | |
| SCHEMBL9566746 | 0.73 | ALDH1A1 (0.38) | ADORA2AKMT2AMAPTAOC3FFAR1 | |
| SCHEMBL28292626 | 0.73 | KMT2A (0.39) | KMT2AMAPTMEN1PARP10AOC3 | |
| SCHEMBL26640548 | 0.72 | SYK (0.39) | ADORA2AKMT2AMAPTMEN1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108593-B | Substituted oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II | 美迪福伦DBT有限公司 | 2020-03-24 | — | — | CN | disclosed |