SCHEMBL28366266 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CTSL	P07711	11/20	0.39

▸	CTSV	O60911	10/20	0.38

▸	CTSS	P25774	10/20	0.38

▸	CTSK	P43235	8/20	0.38

▸	CTSB	P07858	7/20	0.38

▸	ALDH1A1	P00352	2/20	0.38

▸	KMT2A	Q03164	2/20	0.38

▸	SMN1; SMN2	Q16637	2/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	HPGD	P15428	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21895954	1.00	CTSL (0.39)	CTSLCTSVCTSSCTSKCTSB
SCHEMBL20630581	0.90	CTSL (0.46)	CTSLCTSVCTSSCTSKCTSB
SCHEMBL20630582	0.90	CTSL (0.46)	CTSLCTSVCTSSCTSKCTSB
SCHEMBL21950780	0.89	CNR2 (0.36)	CTSSCTSKKMT2AMEN1
SCHEMBL28362291	0.89	CNR2 (0.36)	CTSSCTSKKMT2AMEN1
SCHEMBL21895863	0.89	CTSS (0.43)	CTSLCTSSCTSKCTSBSMN1; SMN2
SCHEMBL21895861	0.89	CTSS (0.43)	CTSLCTSSCTSKCTSBSMN1; SMN2
SCHEMBL21896476	0.85	CTSG (0.35)	CTSSCTSKALDH1A1KMT2ASMN1; SMN2
SCHEMBL28362197	0.85	CTSG (0.35)	CTSSCTSKALDH1A1KMT2ASMN1; SMN2
SCHEMBL21837400	0.83	FOLH1 (0.47)	ALDH1A1KMT2ASMN1; SMN2MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110869544-A	Cyclic peptide compound having high membrane permeability and library containing same	中外制药株式会社	2020-03-06	—	—	CN	disclosed