Phenazine

Phenazine

SCHEMBL28366290

CSCCC(N)C(=O)O.c1ccc2nc3ccccc3nc2c1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.44
FPR1 P21462 2/20 0.43
PKM P14618 2/20 0.42
ALPI P09923 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
SLC7A5 Q01650 1/20 0.42
BHMT Q93088 1/20 0.41
BHMT2 Q9H2M3 1/20 0.41
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
CTSC P53634 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthrene SCHEMBL29137099 0.86 KIF11 (0.45) KIF11PKMALPIPTGS1XIAP
Quinoline SCHEMBL336069 0.86 ALDH1A1 (0.45) KIF11FPR1LMNA
Quinoline SCHEMBL336068 0.86 ALDH1A1 (0.45) KIF11FPR1LMNA
Racemethionine SCHEMBL27686953 0.85 BHMT (0.53) BHMTBHMT2
Racemethionine SCHEMBL28117612 0.84 KIF11 (0.54) KIF11PKMALPIPTGS1XIAP
Methionine SCHEMBL28117610 0.84 KIF11 (0.54) KIF11PKMALPIPTGS1XIAP
Racemethionine SCHEMBL14248767 0.84 KIF11 (0.51) KIF11PKMALPIPTGS1XIAP
Methionine SCHEMBL14248774 0.84 KIF11 (0.51) KIF11PKMALPIPTGS1XIAP
Racemethionine SCHEMBL3066583 0.83 BHMT (0.55) BHMTBHMT2
Racemethionine SCHEMBL28833032 0.83 KIF11 (0.48) KIF11PKMALPIPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107870190-B Genetic biochemical locus marker of cerebral ischemia inbred-line meriones unguiculatus and application thereof 中国人民解放军军事科学院军事医学研究院 2020-02-07 CN claimed
CN-107870190-B Genetic biochemical locus marker of cerebral ischemia inbred-line meriones unguiculatus and application thereof 中国人民解放军军事科学院军事医学研究院 2020-02-07 CN disclosed