Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL336068 | 1.00 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2FPR1GRIN3B | |
| Phenazine SCHEMBL28366290 | 0.86 | KIF11 (0.44) | LMNAFPR1KIF11 | |
| Quinazoline SCHEMBL29022148 | 0.84 | EGFR (0.49) | ALDH1A1SMN1; SMN2FPR1KIF11FNTA | |
| Lysine SCHEMBL12479352 | 0.80 | GSR (0.54) | ALDH1A1GRIN3BGRIN1GRIN2CKIF11 | |
| Phenanthrene SCHEMBL29137099 | 0.79 | KIF11 (0.45) | ALDH1A1KIF11FNTAFNTBKMT2A | |
| Quinoline SCHEMBL10940077 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2GRIN3BGRIN1 | |
| Quinoline SCHEMBL10940079 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2GRIN3BGRIN1 | |
| Quinoline SCHEMBL31053435 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2GRIN3BGRIN1 | |
| Quinoline SCHEMBL7081988 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2KDM4EPRNP | |
| Quinoline SCHEMBL7081987 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2KDM4EPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841744-B1 | 1-PHENYL-3-PIPERAZINE-PYRAZOLES AND PESTICIDAL COMPOSITIONS OF MATTER THEREOF | MERIAL LTD (US) | 2014-09-24 | — | — | EP | disclosed |
| EP-1828140-B1 | 5-AMINOPYRAZOLE DERIVATIVES AS PESTICIDAL COMPOUNDS | MERIAL LTD (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| US-8097732-B2 | e.g. 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(1,3-dithiolan-2-yl)-1H-pyrazole-3-carbonitrile; controlling pests, especially by treatment of domestic animals | MERIAL LIMITED (US) | 2012-01-17 | — | — | US | disclosed |
| EP-1838693-B1 | PYRAZOLE DERIVATIVES AS PESTICIDES | MERIAL LTD (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110265005-A1 | METHOD, SYSTEM AND APPARATUS FOR MANAGING MESSAGE ATTACHMENTS | RESEARCH IN MOTION LIMITED (CA) | 2011-10-27 | — | — | US | disclosed |
| EP-2332937-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330106-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| EP-1824845-B1 | 1-ARYLPYRAZOLES AND THEIR USE AS PESTICIDES | MERIAL LTD (US) | 2011-03-09 | — | — | EP | disclosed |
| EP-1838693-A1 | PYRAZOLE DERIVATIVES AS PESTICIDES | Merial Ltd. (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1828140-A1 | 5-AMINOPYRAZOLE DERIVATIVES AS PESTICIDAL COMPOUNDS | Merial Limited (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1824845-A1 | 1-ARYLPYRAZOLES AND THEIR USE AS PESTICIDES | Merial Ltd. (US) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006119876-A1 | PESTICIDAL SUBSTITUTED PHENYLETHERS | MERIAL LTD. (GR) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006087162-A1 | PESTICIDAL SUBSTITUTED PIPERIDINES | MERIAL LTD. (US) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006079480-A1 | PESTICIDAL SUBSTITUTED THIOETHERS | MERIAL LTD. (US) | 2006-08-03 | — | — | WO | disclosed |
| WO-2006077070-A1 | CHEMICAL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE THEREOF | MERIAL LTD. (US) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006063700-A1 | 1-ARYLPYRAZOLES AND THEIR USE AS PESTICIDES | MERIAL LTD. (US) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006061146-A1 | 5-AMINOPYRAZOLE DERIVATIVES AS PESTICIDAL COMPOUNDS | MERIAL LTD. (US) | 2006-06-15 | — | — | WO | disclosed |
| WO-2006061147-A1 | 1-PHENYL-3-PIPERAZINE-PYRAZOLES AND PESTICIDAL COMPOSITIONS OF MATTER THEREOF | BAYER CROPSCIENCE S. A. (FR) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | ALDH1A1 683/4885LMNA 450/4885SMN1; SMN2 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.