Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364516 | 0.91 | MAPT (0.40) | ALDH1A1MAPTMAPK1GAASLC27A1 | |
| SCHEMBL28364424 | 0.90 | POLB (0.45) | ALDH1A1MAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL28884420 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL28367955 | 0.90 | MAPT (0.42) | ALDH1A1MAPTMAPK1SLC27A1KDM4E | |
| SCHEMBL28364655 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPTMAPK1LMNADRD4 | |
| SCHEMBL28368239 | 0.89 | KMT2A (0.48) | MAPTMAPK1GAAHTR1ADRD4 | |
| SCHEMBL28368628 | 0.87 | KCNA5 (0.40) | ALDH1A1MAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL28391828 | 0.85 | KMT2A (0.50) | ALDH1A1MAPTMAPK1GAALMNA | |
| SCHEMBL28364406 | 0.84 | ADAMTS5 (0.42) | ALDH1A1MAPTMAPK1GAALMNA | |
| SCHEMBL28364477 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTMAPK1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |