Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SOD1 | P00441 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364516 | 0.89 | MAPT (0.40) | KMT2AMEN1GAAMAPTMAPK1 | |
| SCHEMBL28368628 | 0.89 | KCNA5 (0.40) | KMT2AMEN1GAAP4HBMAPT | |
| SCHEMBL28368248 | 0.89 | ALDH1A1 (0.51) | KMT2AMEN1GAAMAPTMAPK1 | |
| SCHEMBL28364424 | 0.89 | POLB (0.45) | KMT2AMEN1MAPTMAPK1HTR1A | |
| SCHEMBL28884420 | 0.89 | ALDH1A1 (0.39) | KMT2AMEN1GAAMAPTMAPK1 | |
| SCHEMBL28367955 | 0.88 | MAPT (0.42) | KMT2AMEN1MAPTMAPK1TSHR | |
| SCHEMBL28364655 | 0.86 | ALDH1A1 (0.41) | MAPTMAPK1POLBDRD4 | |
| SCHEMBL28391953 | 0.85 | L3MBTL1 (0.53) | KMT2AMEN1GAAMAPTMAPK1 | |
| SCHEMBL28364406 | 0.82 | ADAMTS5 (0.42) | KMT2AMEN1GAAMAPTMAPK1 | |
| SCHEMBL28364477 | 0.80 | ALDH1A1 (0.47) | KMT2AMEN1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |