Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364424 | 0.91 | POLB (0.45) | MAPTALDH1A1MAPK1PKMGFER | |
| SCHEMBL28884420 | 0.91 | ALDH1A1 (0.39) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28368248 | 0.91 | ALDH1A1 (0.51) | MAPTALDH1A1MAPK1SLC27A1HTT | |
| SCHEMBL28367955 | 0.91 | MAPT (0.42) | MAPTALDH1A1MAPK1SLC27A1MEN1 | |
| SCHEMBL28368239 | 0.89 | KMT2A (0.48) | MAPTMAPK1GFERMEN1KMT2A | |
| SCHEMBL28364655 | 0.89 | ALDH1A1 (0.41) | MAPTALDH1A1MAPK1CA1CA2 | |
| SCHEMBL28368628 | 0.86 | KCNA5 (0.40) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28364406 | 0.85 | ADAMTS5 (0.42) | MAPTALDH1A1MAPK1HTTMEN1 | |
| SCHEMBL28400024 | 0.85 | LMNA (0.43) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28364477 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |