Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28375664 | 0.87 | KMT2A (0.47) | NR4A2CREBBPALDH1A1KMT2AGPR84 | |
| SCHEMBL28369467 | 0.86 | NR4A2 (0.59) | NR4A2CREBBPALDH1A1RAB9AMAPT | |
| SCHEMBL27586464 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ATMMAPTMEN1KMT2A | |
| SCHEMBL28885915 | 0.81 | NR4A2 (0.50) | NR4A2CREBBPPDE1CALDH1A1RAB9A | |
| SCHEMBL28375303 | 0.80 | GPR84 (0.51) | NR4A2CREBBPPDE1CRAB9AMAPT | |
| SCHEMBL28369568 | 0.79 | GPR84 (0.49) | NR4A2CREBBPPDE1CRAB9AMAPT | |
| SCHEMBL5881120 | 0.77 | NR4A2 (0.55) | NR4A2CREBBPALDH1A1MAPTMEN1 | |
| SCHEMBL8804759 | 0.76 | NR3C1 (0.62) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30031033 | 0.75 | NR4A2 (1.00) | NR4A2CREBBPALDH1A1ATMRAB9A | |
| SCHEMBL1093530 | 0.75 | NR4A2 (1.00) | NR4A2CREBBPALDH1A1ATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149602-B | Application of indole compounds and derivatives thereof in preparation of anti-HIV drugs | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |
| CN-107149603-B | Application of indole compounds and derivatives thereof in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-07-14 | — | — | CN | disclosed |
| CN-107176921-B | Indole compounds with antiviral activity in isatis root and derivatives thereof | 中国医学科学院药物研究所 | 2020-03-31 | — | — | CN | disclosed |