Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 1.00 |
| ▸ | CA1 | P00915 | 13/20 | 1.00 |
| ▸ | MAOA | P21397 | 5/20 | 0.73 |
| ▸ | MAOB | P27338 | 5/20 | 0.73 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18118199 | 0.83 | CA2 (0.73) | CA2CA1CA9CA12 | |
| SCHEMBL28366892 | 0.83 | CA2 (1.00) | CA2CA1MAOAMAOBCA9 | |
| SCHEMBL28366821 | 0.83 | CA2 (0.73) | CA2CA1MAOAMAOB | |
| SCHEMBL28373035 | 0.83 | CA2 (1.00) | CA2CA1MAOAMAOBCA9 | |
| SCHEMBL8633116 | 0.79 | CA2 (0.68) | CA2CA1MAOAMAOB | |
| SCHEMBL9612006 | 0.79 | PKM (0.90) | CA2CA1TP53PKM | |
| SCHEMBL11965041 | 0.79 | PKM (0.90) | CA2CA1TP53PKM | |
| SCHEMBL4883712 | 0.79 | PKM (1.00) | CA2CA1TP53PKM | |
| SCHEMBL28367154 | 0.79 | CA2 (0.78) | CA2CA1MAOAMAOBCA9 | |
| SCHEMBL28884814 | 0.79 | CA2 (1.00) | CA2CA1MAOAMAOBCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903262-A | Oxadiazole substituted benzene sulfonamide compound, preparation method thereof and application of oxadiazole substituted benzene sulfonamide compound as carbonic anhydrase inhibitor | 中国人民解放军军事科学院军事医学研究院 | 2020-03-24 | — | — | CN | claimed |
| CN-110903262-A | Oxadiazole substituted benzene sulfonamide compound, preparation method thereof and application of oxadiazole substituted benzene sulfonamide compound as carbonic anhydrase inhibitor | 中国人民解放军军事科学院军事医学研究院 | 2020-03-24 | — | — | CN | disclosed |