Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373076 | 1.00 | PTGS2 (0.57) | PTGS2USP2MAPK1ALDH1A1GAA | |
| SCHEMBL28373082 | 0.95 | METAP2 (0.52) | PTGS2USP2MAPK1ALDH1A1GAA | |
| SCHEMBL28376474 | 0.95 | MAPK1 (0.54) | PTGS2USP2MAPK1ALDH1A1GAA | |
| SCHEMBL28372567 | 0.92 | SMN1; SMN2 (0.53) | PTGS2USP2MAPK1ALDH1A1GAA | |
| SCHEMBL28376537 | 0.92 | SMN1; SMN2 (0.53) | PTGS2USP2ALDH1A1GAANPSR1 | |
| SCHEMBL28376596 | 0.91 | MEN1 (0.55) | USP2MAPK1ALDH1A1GAANPSR1 | |
| SCHEMBL28372115 | 0.91 | SMN1; SMN2 (0.55) | USP2MAPK1ALDH1A1GAANPSR1 | |
| SCHEMBL28375856 | 0.90 | CYP3A4 (0.52) | PTGS2USP2ALDH1A1GAANPSR1 | |
| SCHEMBL28376399 | 0.90 | TUBB4A (0.56) | USP2MAPK1ALDH1A1GAANPSR1 | |
| SCHEMBL28376572 | 0.90 | TERT (0.60) | USP2MAPK1ALDH1A1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910082-B | 3,4, 5-trisubstituted-1, 2, 4-triazole thioether derivative and synthesis method and application thereof | 贵阳学院 | 2020-03-17 | — | — | CN | disclosed |