Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28371235 | 0.87 | TGM2 (0.52) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL24968537 | 0.81 | P2RX4 (0.51) | EGFR | |
| SCHEMBL183985 | 0.80 | TGM2 (0.54) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL28371190 | 0.80 | TGM2 (0.54) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL28371187 | 0.75 | EGFR (0.60) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL28371176 | 0.75 | TGM2 (0.48) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL12420708 | 0.74 | PARP15 (0.58) | ACACBPARP15PARP10PARP2 | |
| SCHEMBL23747582 | 0.73 | RAB9A (0.53) | LMNAMAPT | |
| SCHEMBL1858579 | 0.73 | PARP15 (0.57) | LMNAPARP15PARP10PARP2FNTA | |
| SCHEMBL8548307 | 0.73 | TGM2 (0.68) | TGM2LMNAF13A1TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981876-B | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110981876-A | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-04-10 | — | — | CN | disclosed |