Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27897350 | 0.85 | GPR84 (0.58) | GPR84NR4A2SLC6A4IDO1HTR2A | |
| SCHEMBL28759115 | 0.81 | GPR84 (0.53) | GPR84NR4A2ALDH1A1SLC6A4IDO1 | |
| SCHEMBL27994549 | 0.78 | GPR84 (0.58) | GPR84HTR2ATDO2 | |
| SCHEMBL28078767 | 0.77 | GPR84 (0.49) | GPR84NR4A2ALDH1A1SLC6A4IDO1 | |
| SCHEMBL28611191 | 0.76 | GPR84 (0.47) | GPR84NR4A2ALDH1A1SLC6A4IDO1 | |
| SCHEMBL24819171 | 0.75 | KIF11 (0.45) | ALDH1A1DYRK1AHTR2AGSK3BKDM4E | |
| SCHEMBL26795648 | 0.75 | HTR1D (0.47) | ALDH1A1TDO2 | |
| SCHEMBL30382234 | 0.75 | GPR84 (0.58) | GPR84NR4A2ALDH1A1SLC6A4IDO1 | |
| SCHEMBL8268363 | 0.75 | GPR84 (0.58) | GPR84NR4A2ALDH1A1SLC6A4IDO1 | |
| SCHEMBL8049566 | 0.74 | TGFBR1 (0.46) | GPR84NR4A2ALDH1A1SLC6A4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |