Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611191 | 0.84 | GPR84 (0.47) | GPR84GRM4NR4A2GAAMAPT | |
| SCHEMBL8056408 | 0.82 | TDO2 (0.48) | TGFBR1GPR84TDO2CYP1A2CYP2C8 | |
| SCHEMBL8051654 | 0.78 | KIF11 (0.47) | DYRK1AGSK3BGAAMAPTJAK2 | |
| SCHEMBL5618628 | 0.78 | IMPDH2 (0.53) | TGFBR1ADRA2AGAAMAPTATM | |
| SCHEMBL12845523 | 0.77 | GPR84 (0.51) | TGFBR1GPR84TDO2DYRK1AGSK3B | |
| SCHEMBL12845601 | 0.75 | GPR84 (0.49) | GPR84SLC6A4 | |
| SCHEMBL28375689 | 0.74 | GPR84 (0.58) | GPR84TDO2DYRK1ANR4A2GSK3B | |
| SCHEMBL7335273 | 0.73 | SPR (0.44) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| Maleic Acid SCHEMBL8049580 | 0.72 | TDO2 (0.54) | TGFBR1TDO2ALDH1A1CYP1A2CYP2C8 | |
| Fumaric Acid SCHEMBL8049585 | 0.72 | TDO2 (0.54) | TGFBR1TDO2ALDH1A1CYP1A2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | claimed |
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |