Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371261 | 0.84 | TRPM8 (0.45) | TRPM8HSD11B1MLYCDALDH1A1MAPT | |
| SCHEMBL28320439 | 0.84 | TRPM8 (0.45) | TRPM8HSD11B1MLYCDALDH1A1MAPT | |
| SCHEMBL10904843 | 0.82 | TRPM8 (0.59) | TRPM8ALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL28182286 | 0.82 | TRPM8 (0.59) | TRPM8ALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL28336781 | 0.82 | CA1 (0.46) | ALDH1A1MAPTHPGDCYP3A4BLM | |
| SCHEMBL28266347 | 0.81 | TRPM8 (0.43) | TRPM8HSD11B1MLYCDALDH1A1MAPT | |
| SCHEMBL9508600 | 0.81 | TRPM8 (0.47) | TRPM8ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL19418154 | 0.80 | NPSR1 (0.37) | TRPM8MLYCDALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4000774 | 0.80 | KDM4E (0.47) | MLYCDALDH1A1TSHRHPGDCYP3A4 | |
| SCHEMBL18988683 | 0.80 | MLYCD (0.48) | TRPM8HSD11B1MLYCDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445920-A | A kind of production method of bentazone raw pesticide | 江苏绿叶农化有限公司 | 2017-12-08 | — | — | CN | claimed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |
| CN-107445920-A | A kind of production method of bentazone raw pesticide | 江苏绿叶农化有限公司 | 2017-12-08 | — | — | CN | disclosed |
| WO-2010115264-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | WO | disclosed |
| EP-2004615-A2 | QUINAZOLINES FOR PDK1 INHIBITION | Novartis AG (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007117607-A9 | QUINAZOLINES FOR PDK1 INHIBITION | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2007117607-A2 | QUINAZOLINES FOR PDK1 INHIBITION | NOVARTIS AG (CH) | 2007-10-18 | — | — | WO | disclosed |
| US-6904423-B1 | Method and system for artificial intelligence directed lead discovery through multi-domain clustering | BIOREASON, INC. (US) | 2005-06-07 | — | — | US | disclosed |
| US-20040117164-A1 | Method and system for artificial intelligence directed lead discovery in high throughput screening data | BIOREASON, INC. | 2004-06-17 | — | — | US | disclosed |
| US-6625585-B1 | Method and system for artificial intelligence directed lead discovery though multi-domain agglomerative clustering | BIOREASON, INC. | 2003-09-23 | — | — | US | disclosed |
| US-5354762-A | Insecticides | ROHM AND HAAS COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0261755-B1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVES OF N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-12-16 | — | — | EP | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0480661-A1 | Insecticidal ferrocenoyl acylhydrazines | ROHM AND HAAS COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| US-5075471-A | Plant destroying insects | ROHM AND HAAS COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0261755-A2 | Five-membered heterocyclic derivatives of N'-substituted-N,N'-Diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-03-30 | — | — | EP | disclosed |
| EP-0253468-A2 | Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |