Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401811 | 0.84 | CTNNB1 (0.58) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL28378307 | 0.83 | CTNNB1 (0.56) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL4129944 | 0.82 | CTNNB1 (0.70) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| Zinc Ion SCHEMBL11875746 | 0.82 | CTNNB1 (0.70) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL11122294 | 0.82 | CTNNB1 (0.70) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL17888701 | 0.82 | CTNNB1 (0.70) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL11407863 | 0.82 | CTNNB1 (0.70) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL7595866 | 0.82 | CTNNB1 (0.70) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| Lithium Ion SCHEMBL20490067 | 0.82 | CTNNB1 (0.70) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL9244300 | 0.81 | CTNNB1 (0.54) | CTNNB1SMN1; SMN2L3MBTL1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110960437-A | Dandruff-removing hair washing bubbles and preparation method thereof | 威莱(广州)日用品有限公司 | 2020-04-07 | — | — | CN | disclosed |