Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.40 |
| ▸ | CES1 | P23141 | 6/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286444 | 0.88 | FAAH (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28523113 | 0.84 | FAAH (0.41) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL5940751 | 0.78 | FAAH (0.38) | FAAHCES1CES2MEN1KMT2A | |
| Palmitamide SCHEMBL28694450 | 0.77 | TP53 (0.47) | FAAHMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL2780739 | 0.77 | FAAH (0.46) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28363537 | 0.77 | FAAH (0.46) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL7570977 | 0.77 | FAAH (0.46) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL4674959 | 0.75 | LMNA (0.57) | MEN1KMT2ACYP1A2TP53LMNA | |
| SCHEMBL9186561 | 0.75 | TP53 (0.42) | TP53CA12CA2CA7CA9 | |
| SCHEMBL28336601 | 0.75 | FAAH (0.43) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112165928-A | Temperature-sensitive cosmetic | 株式会社资生堂 | 2021-01-01 | — | — | CN | disclosed |
| CN-112165932-A | Temperature-sensitive cosmetic | 株式会社资生堂 | 2021-01-01 | — | — | CN | disclosed |
| CN-111032000-A | Water-in-oil type emulsion cosmetic | 株式会社资生堂 | 2020-04-17 | — | — | CN | disclosed |