Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.41 |
| ▸ | CES1 | P23141 | 6/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5940751 | 0.87 | FAAH (0.38) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28951894 | 0.86 | FAAH (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28380134 | 0.84 | FAAH (0.40) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28363537 | 0.81 | FAAH (0.46) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28336601 | 0.79 | FAAH (0.43) | FAAHCES1CES2MEN1KMT2A | |
| Palmitamide SCHEMBL28694450 | 0.78 | TP53 (0.47) | FAAHMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL19409848 | 0.78 | FAAH (0.42) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28646473 | 0.78 | FAAH (0.42) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28363752 | 0.77 | FAAH (0.39) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL26638038 | 0.77 | FAAH (0.39) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377224-B | Dyeing composition | 莱雅公司 | 2021-02-12 | — | — | CN | disclosed |