Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.38 |
| ▸ | CES1 | P23141 | 5/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12494324 | 0.89 | FAAH (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28523113 | 0.87 | FAAH (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| Palmitamide SCHEMBL28694450 | 0.78 | TP53 (0.47) | FAAHMEN1CYP1A2KMT2ATP53 | |
| SCHEMBL28363537 | 0.78 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28380134 | 0.78 | FAAH (0.40) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28363752 | 0.77 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL26638038 | 0.77 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL29005882 | 0.76 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28608284 | 0.76 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28336601 | 0.76 | FAAH (0.43) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060057096-A1 | Cosmetic composition comprising at least one cationic surfactant, at least one aminated silicone, at least one fatty alcohol, and at least one diol | L'OREAL S.A. (FR) | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060057096-A1 | Cosmetic composition comprising at least one cationic surfactant, at least one aminated silicone, at least one fatty alcohol, and at least one diol | SGMS1, SGMS2, CUTA | FAAH 84/4885CES1 1567/4885CES2 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.