SCHEMBL28381979

SCHEMBL28381979

CCC(c1ccccc1)C(C(C)C)C(CCC(=O)O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 4/20 0.40
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
FFAR1 O14842 2/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.39
USP5 P45974 1/20 0.39
CPA3 P15088 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
NR4A2 P43354 1/20 0.38
POLB P06746 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26269478 0.83 TAAR1 (0.53) TAAR1MEN1KMT2AALDH1A1CYP1A2
SCHEMBL27580075 0.81 MEN1 (0.44) HKDC1MEN1KMT2ALMNAHSD17B10
SCHEMBL28378824 0.80 HKDC1 (0.45) HKDC1MEN1KMT2ALMNAHSD17B10
SCHEMBL28382136 0.77 HKDC1 (0.42) HKDC1MEN1KMT2ALMNAHSD17B10
SCHEMBL8849672 0.77 HKDC1 (0.42) HKDC1MEN1KMT2ALMNAHSD17B10
SCHEMBL10903498 0.75 GABBR2 (0.44) TAAR1ALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL7712809 0.75 TAAR1 (0.48) TAAR1MEN1KMT2AALDH1A1CYP1A2
SCHEMBL3056333 0.74 GABBR2 (0.47) MEN1KMT2ALMNAHSD17B10ALDH1A1
SCHEMBL7051893 0.74 ACE (0.40) HKDC1LMNAHSD17B10ALDH1A1CYP1A2
SCHEMBL242853 0.73 RIPK1 (0.52) TAAR1ALDH1A1CYP1A2CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
CN-110950984-B Catalyst component for olefin polymerization, catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN disclosed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN disclosed
CN-110950984-A Catalyst component for olefin polymerization, catalyst and olefin polymerization method 中国石油化工股份有限公司 2020-04-03 CN disclosed