Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | JAK3 | P52333 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.40 |
| ▸ | GPR39 | O43194 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | DCK | P27707 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177368 | 0.82 | HRH3 (0.61) | HRH3TSHRSMN1; SMN2 | |
| SCHEMBL16684935 | 0.78 | HRH3 (0.40) | HRH3 | |
| SCHEMBL29283185 | 0.78 | LMNA (0.41) | HRH3LOXL2DCK | |
| SCHEMBL16684964 | 0.76 | GPR119 (0.53) | HRH3 | |
| SCHEMBL19658510 | 0.76 | OPRD1 (0.47) | JAK2JAK3NPC1TSHRRECQL | |
| SCHEMBL17077859 | 0.76 | CYP2C19 (0.53) | HRH3DCK | |
| SCHEMBL28913940 | 0.75 | HRH3 (0.56) | HRH3TSHR | |
| SCHEMBL17754138 | 0.74 | HRH4 (0.51) | NPC1TSHRRECQLRAB9ASMN1; SMN2 | |
| SCHEMBL29283189 | 0.74 | KDM4E (0.57) | TSHR | |
| SCHEMBL19652240 | 0.73 | TAF1 (0.42) | JAK2JAK3LRRK2HRH4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108613-B | Bromodomain inhibitors and uses thereof | 基因泰克公司 | 2020-02-25 | — | — | CN | disclosed |