Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657904 | 0.87 | MLNR (0.53) | GAAMLNRMEN1KMT2AL3MBTL1 | |
| SCHEMBL28384262 | 0.84 | TLR2 (0.49) | MAOBGAAMLNRL3MBTL1EGFR | |
| SCHEMBL28245547 | 0.84 | TSHR (0.49) | MLNRMEN1KMT2ACYP19A1MMP2 | |
| SCHEMBL28389513 | 0.83 | TXNRD1 (0.42) | MLNRMEN1KMT2AEGFRERBB2 | |
| SCHEMBL28245563 | 0.83 | ALDH1A1 (0.46) | MAOBGAAMLNRKMT2AEGFR | |
| SCHEMBL28384301 | 0.81 | MLNR (0.53) | GAAMLNRMEN1KMT2AL3MBTL1 | |
| SCHEMBL28246432 | 0.81 | LMNA (0.50) | MAOBSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28386527 | 0.81 | PLCG1 (0.46) | GAASMN1; SMN2MLNRMEN1KMT2A | |
| SCHEMBL28390374 | 0.76 | PSEN1 (0.41) | GAASMN1; SMN2MLNRMEN1KMT2A | |
| SCHEMBL779990 | 0.76 | L3MBTL1 (0.55) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892471-B | Substance having protein tyrosine kinase inhibitory activity, preparation method and use thereof | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 2020-03-27 | — | — | CN | disclosed |